Oct 11, 2005 · Background. Adult onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown aetiology that is responsible for a significant proportion of cases of fever of unknown origin and can also have serious musculoskeletal sequelae.Cited by: 397. (See "Treatment of adult Still's disease".) ETIOLOGY. The etiology of adult Still's disease (ASD) is unknown; both genetic factors and a variety of infectious triggers have been suggested as important, but there has been no proof of an infectious etiology, and the evidence supporting a .
Feb 08, 2018 · Still's disease is also referred to as systemic-onset juvenile idiopathic arthritis. Still's disease was first described in children, but it is now known to occur, much less commonly, in adults (in whom it is referred to as adult-onset Still's disease or AOSD). Still's disease is named after the English physician Sir George F. Still (1861-1941). Adult Still disease is a severe version of juvenile idiopathic arthritis (JIA), which occurs in children. Adults can have the same condition, although it is much less common. It is also called adult-onset .
What is the cause of adult-onset Still disease? The exact cause of adult-onset Still disease is not known. One theory is that the disease is caused by infection.Another theory is that Still disease is a hypersensitive or autoimmune disorder (this is where the body's immune system which normally fights off infections or illness suddenly starts to attack the body's cells and tissues it is.